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1

Some recent applications of α-amino nitrile chemistry

Enders, Dieter, Shilvock, John P.

Journal:

Chemical Society Reviews

Year:

2000

Language:

english

File:

PDF, 682 KB

english, 2000

2

ChemInform Abstract: Inhibition of Naringinase (L-Rhamnosidase) by Piperidine Analogues of L-Rhamnose: Scaffolds for Libraries Incorporating Trihydroxypipecolic Acids.

J. P. SHILVOCK, J. R. WHEATLEY, B. DAVIS, R. J. NASH, R. C. GRIFFITHS, M. G. JONES, M. MUELLER, S. CROOK, D. J. WATKIN, C. SMITH, G. S. BESRA, P. J. BRENNAN, G. W. J. FLEET

Journal:

Year:

1997

File:

PDF, 32 KB

1997

3

ChemInform Abstract: The Synthesis of Deoxygalactostatin and 2,6-Imino-heptitol Derivatives via Stannane Mediated Hydroxymethylation of 5-Azido-1,4-lactones.

J. P. SHILVOCK, G. W. J. FLEET

Journal:

Year:

1998

File:

PDF, 35 KB

1998

4

ChemInform Abstract: Intermediates for Incorporation of Tetrahydroxypipecolic Acid Analogues of α- and β-D-Mannopyranose into Combinatorial Libraries: Unexpected Nanomolar-Range Hexosaminidase Inhibitors. Synthesis of α- and β-Homomannojirimycin.

John P. Shilvock, Robert J. Nash, Janet D. Lloyd, Ana L. Winters, Naoki Asano, George W. J. Fleet

Journal:

Year:

1999

Language:

english

File:

PDF, 38 KB

english, 1999

5

ChemInform Abstract: Synthesis of an Eight-Carbon Homologue of α-Homomannojirimycin via a Bicyclic Aminolactone.

John P. Shilvock, Kenneth Y. Hsia, Robert J. Nash, Janet D. Lloyd, Ana L. Winters, Naoki Asano, George W. J. Fleet

Journal:

Year:

1999

File:

PDF, 33 KB

1999

6

ChemInform Abstract: Asymmetric Nucleophilic α-Amino-acylation with Metalated Chiral Amino Nitriles: Enantioselective Synthesis of 3-Substituted 5-Amino-4-oxo-esters via Asymmetric Michael Addition.

Dieter Enders, John P. Shilvock, Gerhard Raabe

Journal:

Year:

1999

File:

PDF, 35 KB

1999

7

ChemInform Abstract: Piperidine Analogues of D-Galactose as Potent Inhibitors of α-Galactosidase: Synthesis by Stannane-Mediated Hydroxymethylation of 5-Azido-1,4-lactones. Structural Relationships Between D-Galactosidase and L-Rhamnosidase Inhibitors.

John P. Shilvock, Robert J. Nash, Alison A. Watson, Ana L. Winters, Terry D. Butters, Raymond A. Dwek, David A. Winkler, George W. J. Fleet

Journal:

Year:

2000

File:

PDF, 31 KB

2000

8

ChemInform Abstract: Synthesis of Homorhamnojirimycins (I) and Related Trihydroxypipecolic Acid Derivatives (II) and (III) via Divergent Bicyclic Amino Lactone Intermediates: Inhibition of Naringinase (L-Rhamnosidase) and dTDP-Rhamnose Biosynthesis.

John P. Shilvock, Joseph R. Wheatley, Robert J. Nash, Alison A. Watson, Rhodri C. Griffiths, Terry D. Butters, Mathias Mueller, David J. Watkin, David A. Winkler, George W. J. Fleet

Journal:

Year:

2000

File:

PDF, 29 KB

2000

9

ChemInform Abstract: Asymmetric Synthesis of β-Lactams and Pseudopeptides via Stereoselective Conjugate Additions of Lithium (α-Methylbenzyl)allylamide to α,β-Unsaturated Iron Acyl Complexes.

Stephen G. Davies, Narciso M. Garrido, Paul A. McGee, John P. Shilvock

Journal:

Year:

2000

File:

PDF, 34 KB

2000

10

ChemInform Abstract: Some Recent Applications of α-Amino Nitrile Chemistry

Dieter Enders, John P. Shilvock

Journal:

Year:

2000

File:

PDF, 26 KB

2000

11

Inhibition of naringinase (L-rhamnosidase) by piperidine analogues of L-rhamnose: Scaffolds for libraries incorporating trihydroxypipecolic acids

John P. Shilvock, Joseph R. Wheatley, Benjamin Davis, Robert J. Nash, Rhodri C. Griffiths, M.George Jones, Matthias Müller, Sarah Crook, David J. Watkin, Colin Smith, Gurdyal S. Besra, Patrick J. Bren

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 305 KB

english, 1996

12

Intermediates for incorporation of tetrahydroxypipecolic acid analogues of α- and β-d-mannopyranose into combinatorial libraries: unexpected nanomolar-range hexosaminidase inhibitors. Synthesis of α- and β-homomannojirimycin

John P Shilvock, Robert J Nash, Janet D Lloyd, Ana L Winters, Naoki Asano, George W.J Fleet

Journal:

Tetrahedron: Asymmetry

Year:

1998

Language:

english

File:

PDF, 299 KB

english, 1998

13

Synthesis of an eight carbon homologue of α-homomannojirimycin via a bicyclic aminolactone

John P. Shilvock, Kenneth Y. Hsia, Robert J. Nash, Janet D. Lloyd, Ana L. Winters, Naoki Asano, George W.J. Fleet

Journal:

Tetrahedron: Asymmetry

Year:

1998

Language:

english

File:

PDF, 151 KB

english, 1998

14

Piperidine analogues of D-galactose as potent inhibitors of α-galactosidase: Synthesis by stannane-mediated hydroxymethylation of 5-azido-1,4-lactones. Structural relationships between D-galactosidase and L-rhamnosidase inhibitors

Shilvock, John P., Nash, Robert J., Watson, Alison A., Winters, Ana L., Butters, Terry D., Dwek, Raymond A., Winkler, David A., Fleet, George W. J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1999

Language:

english

File:

PDF, 211 KB

english, 1999

15

THE PYROGENETIC ACTION OF SULPHUR IN OLIVE OIL

Journal:

Year:

1930

Language:

english

File:

PDF, 324 KB

english, 1930

16

Asymmetric nucleophilic α-amino-acylation with metalated chiral amino nitriles: enantioselective synthesis of 3-substituted 5-amino-4-oxo-esters via asymmetric Michael addition

Enders, Dieter, Shilvock, John P., Raabe, Gerhard

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1999

Language:

english

File:

PDF, 135 KB

english, 1999

17

Synthesis of homorhamnojirimycins and related trihydroxypipecolic acid derivatives via divergent bicyclic amino lactone intermediates: Inhibition of naringinase (L-rhamnosidase) and dTDP-rhamnose biosynthesis

Shilvock, John P., Wheatley, Joseph R., Nash, Robert J., Watson, Alison A., Griffiths, Rhodri C., Butters, Terry D., Müller, Mathias, Watkin, David J., Winkler, David A., Fleet, George W. J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1999

Language:

english

File:

PDF, 271 KB

english, 1999

18

Asymmetric synthesis of β-lactams and pseudopeptides via stereoselective conjugate additions of lithium (α-methylbenzyl)allylamide to α,β-unsaturated iron acyl complexes

Davies, Stephen G., Garrido, Narciso M., McGee, Paul A., Shilvock, John P.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1999

Language:

english

File:

PDF, 156 KB

english, 1999

19

The Left-Right Pitx2 Pathway Drives Organ-Specific Arterial and Lymphatic Development in the Intestine

Mahadevan, Aparna, Welsh, Ian C., Sivakumar, Aravind, Gludish, David W., Shilvock, Abigail R., Noden, Drew M., Huss, David, Lansford, Rusty, Kurpios, Natasza A.

Journal:

Developmental Cell

Year:

2014

Language:

english

File:

PDF, 8.76 MB

english, 2014

20

The Synthesis of Deoxygalactostatin and 2,6-Imino-heptitol Derivatives via Stannane Mediated Hydroxymethylation of 5-Azido-1,4-lactones

Shilvock, John P., Fleet, George W. J.

Journal:

Year:

1998

Language:

english

File:

PDF, 69 KB

english, 1998

21

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown

Chung, Hachung, Calis, Jorg J.A., Wu, Xianfang, Sun, Tony, Yu, Yingpu, Sarbanes, Stephanie L., Dao Thi, Viet Loan, Shilvock, Abigail R., Hoffmann, H.-Heinrich, Rosenberg, Brad R., Rice, Charles M.

Journal:

Year:

2018

Language:

english

File:

PDF, 8.74 MB

english, 2018